Dave Bondy
Politics • Culture • News
Lingering Spike Protein in Some Vaccine Recipients Linked to Chronic Illness, Yale Study Finds
Mystery symptoms linger after vaccination, leaving experts searching for answers.
February 23, 2025
post photo preview

NEW HAVEN, Conn. – Yale researchers are investigating a puzzling condition in which some individuals develop lingering symptoms after receiving COVID-19 vaccinations. The study, led by Yale School of Medicine’s Akiko Iwasaki and Harlan Krumholz, examines changes in the immune system that may be linked to these ongoing complaints.

The research, part of Yale’s Listen to Immune, Symptom and Treatment Experiences Now (LISTEN) Study, looked at blood samples from people reporting symptoms such as fatigue, brain fog, dizziness, insomnia and exercise intolerance soon after vaccination. The findings suggest that components of the immune response—along with traces of the vaccine’s spike protein—may be connected to the unexplained, persistent symptoms.

When I was part of the mainstream media, I couldn’t cover stories like this. Now, as an independent journalist, I’m committed to bringing you the unfiltered truth—and I need your help. For just $6 a month, you can become a paid subscriber and support my mission to deliver honest, fearless reporting. You can cancel anytime, but together, we can make a real difference. I can’t do this without you.

 

 

“We’re beginning to see that the immune system in some people might not be returning to its usual state after vaccination,” said Harlan Krumholz, Harold H. Hines, Jr. Professor of Medicine (Cardiology) at Yale School of Medicine. “This study is our first step in trying to understand what might be driving these symptoms.”

Researchers compared blood samples from 42 individuals who reported these chronic symptoms with samples from 22 individuals who did not experience any lingering issues after vaccination. They noted differences in the immune cells between the two groups. In those with ongoing symptoms, there were fewer effector CD4+ T cells—an important part of the body’s defense system—and an increase in TNF-alpha–positive CD8 T cells, which are linked to inflammation. These changes point to an altered immune response that could be fueling the symptoms.

Another significant finding was related to the vaccine’s spike protein. COVID-19 vaccines work by teaching the immune system to recognize the spike protein, a component of the virus. Normally, the spike protein is cleared from the bloodstream within a few days after vaccination. However, the Yale study found that some individuals had measurable levels of the spike protein more than 700 days after their last shot.

“That was surprising, to find spike protein in circulation at such a late time,” said Akiko Iwasaki, Sterling Professor of Immunobiology at Yale School of Medicine. “We don’t yet know if the persistent spike protein is directly causing the symptoms, but its presence might be one of the pieces of the puzzle.”

Subscribed

The study also noted that participants who had not been infected with COVID-19 had lower levels of antibodies against the spike protein compared to others. Researchers believe this difference could be linked to the number of vaccine doses received, as fewer doses would give the body less opportunity to develop antibodies.

Experts say that the condition, which some are calling post-vaccination syndrome (PVS), may share similarities with other post-infectious syndromes where chronic symptoms arise from a disrupted immune system or even from reactivation of dormant viruses. In this study, evidence suggested that some individuals with these lingering symptoms were more likely to show signs of Epstein-Barr virus reactivation, a virus known to cause mononucleosis.

“Different people might experience these symptoms for different reasons,” Krumholz explained. “For some, it might be an issue of immune dysregulation. For others, it could be related to a virus that has reawakened. We need to carefully map out these pathways to really understand what’s going on.”

The Yale team stresses that their findings are preliminary. More research is needed to confirm the immune changes observed and to determine exactly how—or if—they contribute to the ongoing symptoms. They plan to study larger groups of patients to see if the patterns hold true and to explore additional factors that might be at work, such as autoimmunity or tissue damage.

 

 

“If we can figure out why the spike protein is lingering for so long in some people, we might be able to remove it,” Iwasaki said. “That could open the door to treatments that might reduce or even eliminate these chronic symptoms.”

The study, published as a preprint on MedRxiv on Feb. 19, has already sparked discussion among clinicians and researchers who are keen to understand the full range of responses to COVID-19 vaccinations. While vaccination remains a crucial tool in the fight against COVID-19, understanding and addressing any potential adverse effects is equally important for public health.

For many, the symptoms of PVS are more than just a nuisance—they interfere with everyday activities. People have reported being unable to exercise, having difficulty concentrating at work, and struggling with sleep, which in turn can lead to anxiety and a decreased quality of life. The Yale study offers a glimpse into the complex biology that may be behind these issues and underscores the importance of further investigation.

“Our goal is to use rigorous science to give voice to people who are experiencing these symptoms,” said Krumholz. “It’s about ensuring that every patient’s experience is validated and that we eventually develop the tools to diagnose and treat this condition.”

As researchers continue to work on these questions, the hope is that a better understanding of PVS will not only lead to improved treatment for those suffering from chronic symptoms but also guide future vaccine development to minimize any unintended side effects. For now, the Yale study serves as a reminder that even well-established medical interventions warrant ongoing study to ensure that every individual’s health is safeguarded.

For more information and updates on this study, visit Yale School of Medicine’s website or follow updates on MedRxiv.

 

 

 

 
 
community logo
Join the Dave Bondy Community
To read more articles like this, sign up and join my community today
1
What else you may like…
Videos
Posts
Articles
September 25, 2025
School board bans clapping....seriously

ALPENA, Mich. — A new rule banning applause and other displays of emotion at Alpena Public Schools board meetings has sparked pushback from community members who say the policy infringes on their free speech rights.

The board recently adopted a policy prohibiting clapping, cheering, booing, or any demonstrations from audience members during meetings. Board President Eric Lawson said the restriction is meant to prevent disruptions and maintain order.

“We’re doing our best to show respect to you all and make sure you have adequate time for your comments,” Lawson said during a recent meeting. “Please show the board a little respect as well.”

Not everyone in attendance agreed. Several residents voiced frustration, including one woman who argued that clapping constitutes symbolic speech protected under the First Amendment.

“Clapping is a universal symbolic action that typically expresses approval,” she said. “Up until one week ago, clapping was a regular occurrence at these ...

00:02:38
September 22, 2025
Tensions flare at the Grand Ledge, Michigan school board meeting as parents clash over whether a teacher should be fired for a social media post about Charlie Kirk. Some demanded his removal, while others defended his right to speak out.

Tensions flare at the Grand Ledge, Michigan school board meeting as parents clash over whether a teacher should be fired for a social media post about Charlie Kirk. Some demanded his removal, while others defended his right to speak out.

00:01:43
September 15, 2025
The chants of “Charlie, Charlie” were echoed by a huge crowd during a vigil at Oakland University in Rochester, Michigan. charliekirk charliekirkvigil

The chants of “Charlie, Charlie” were echoed by a huge crowd during a vigil at Oakland University in Rochester, Michigan. #charliekirk #charliekirkvigil

00:00:15
September 23, 2025
Want to help keep this show going?

Become a paid supporter. I can't keep doing this without you.

September 22, 2025
President Trump on Tylenol "Don't take it"

President Trump on Tylenol "Don't take it"

September 22, 2025
BREAKING: Disney just announced Jimmy Kimmel’s show returns tomorrow.

BREAKING: Disney just announced Jimmy Kimmel’s show returns tomorrow.

post photo preview
September 28, 2025
post photo preview
Mass shooting at Michigan church
The very latest

GRAND BLANC TWP, Mich — A Sunday morning worship service at a Mormon church in Grand Blanc Township turned tragic when a gunman rammed his vehicle into the building, opened fire, and sparked a blaze. Authorities say multiple people were shot and the suspect was “down” after law enforcement engaged him.

The incident unfolded just before 10:30 a.m. at the Church of Jesus Christ of Latter-day Saints, when a 40-year-old man from Burton is alleged to have driven into the front doors of the church. He then exited the vehicle and began firing rounds into the congregation.

 

Grand Blanc Township Police Chief William Renye said two responding officers confronted the shooter, leading to an exchange of gunfire. The suspect was killed. He was reportedly armed with what appeared to be an assault rifle.

If you are not yet a paid subscriber consider becoming one to support my independent journalism for less than $1 per week.

 

 

 

At least ten victims were transported to local hospitals — among them at least one person who died. Chief Renye warned more victims may be discovered once responders can search areas affected by the fire, saying “there may be people up there … that were unable to get out of the church.”

The suspects truck had American flag on the back of the truck.

 

Law enforcement confirmed that there is no ongoing threat to the public. The fire that broke out in the building was still burning as responders rushed to contain it.

Federal agencies including the FBI and ATF were dispatched to the scene to assist state and local authorities. Officials have not yet released a motive or full identity of the shooter.

The State Police bomb squad is at the home of the suspect. I have been told the name of the person who is believed to be the shooter but I am not releasing it until I can confirm it with law enforcement.

 

In the wake of the attack, national figures responded with condemnation and prayers. President Donald Trump called it a “targeted attack on Christians” and said he had been briefed on the situation. Vice President J.D. Vance and U.S. Attorney General Pam Bondi also expressed support and sorrow, with Bondi calling the violence at a place of worship “heartbreaking and chilling.”

 

The local congregation released a statement calling the event a “tragic act of violence,” expressing gratitude to the first responders and pledging cooperation with investigators.

 
 
 
 
 
 
 
Read full Article
September 26, 2025
post photo preview
URGENT: Florida amber alert

DUNNELLON, Fla. — Authorities in Marion County are intensifying their search for a 17-year-old boy who disappeared after a reported shooting Thursday afternoon, sparking a statewide Amber Alert.

Deputies say Caden Speight, 17, was last seen around 4 p.m. near the 12800 block of Southwest Highway 484 in Dunnellon. Investigators believe he was wounded before vanishing.

 
 

The Florida Department of Law Enforcement says Speight may be traveling with four unknown males, possibly Hispanic, in a light-colored van. His disappearance has prompted an urgent search involving helicopters, K-9 units and law enforcement partners across the state.

Speight is described as 6 feet tall, about 150 pounds, with brown hair and brown eyes. He was last seen wearing blue jeans and a T-shirt of an unknown color.

Marion County deputies found a vehicle connected to the incident with a bullet hole, but the teen was not inside. Officials say they are still working to determine how the shooting and the missing persons case are connected.

The Uvalde Foundation for Kids, a nonprofit crisis response group, announced it is offering a $1,000 reward for information leading to Speight’s safe return. The group is also mobilizing volunteers to help distribute flyers in the community.

Anyone with information is urged to call 911, contact the Marion County Sheriff’s Office at 352-732-9111, or reach the FDLE Missing Endangered Persons Clearinghouse at 1-888-FL-MISSING.

Read full Article
September 25, 2025
News they don't want you to see
Thursday September 25, 2025

I don’t let my kids have cell phones. I give them Rapid Radios — Push to Talk Walkie talkies with nationwide coverage. I talked to the owner of the company. Click here to learn more.

 

Click here to order and get an extra 10% off.

 
 

Michigan Appeals Court Rules Grandparents Entitled to Hearing in Visitation Disputes

LANSING, Mich. (Michigan News Source) – Michigan law has a “grandparenting time” rule that lets grandparents ask the court for visitation with their grandchildren in certain situations. This law explains how grandparents can file affidavits, request hearings, and present evidence in court.

When grandparents can step in.

Under Michigan law, grandparents can ask a court for visitation under specific circumstances. These include when the child’s parents are divorcing or already divorced, legally separated, or their marriage has been annulled.

Grandparents may also petition if one of the child’s parents has died, if the parents were never married and live apart but paternity has been legally established, or if the child is living with someone other than a parent. Click here to read more.

 

Suspect charged with attempted murder after stabbing man in back aboard NY train

A 25-year-old man was stabbed multiple times in the back with “an unknown object” while aboard a train New York train, according to authorities.

The suspect was identified as Louis Pallchisaca, 21, a spokesperson with the Office of the Deputy Commissioner, Public Information (DCPI) told The National News Desk.

Pallchisaca was arrested on Wednesday and charged with attempted murder and assault, according to DCPI.

The man was attacked Sunday night shortly after 11:30 p.m. on the No. 7 train at the 111th Street station in Corona, Queens, the spokesperson said.

The spokesperson said the man was “conscious and alert” when police arrived at the scene, adding that he was taken to New York Presbyterian Hospital-Queens in stable condition.

Citing an unnamed police source, The New York Post identified the man who was stabbed as Roberto Gaspar. The media outlet said one of Gaspar’s friends claimed Gaspar “was simply looking down at his phone” when a stranger approached him from behind and attacked him. Click here to read more.

 

The Truth About Michigan’s School Education Budget

There’s a lot for local school administrators to like in the budget the Michigan House passed in August. But they don’t seem to want to see it.

The House budget increases education spending in Michigan more than does the budget passed by the state Senate or the budget proposed by Gov. Gretchen Whitmer. At the same time, it eliminates a host of categorical grants (or “special programs”) that fund outside priorities such as special education, infrastructure spending, smaller class sizes, mental health and other areas. By transferring some of this money to the general education grant, the House budget lets school district officials figure out how they want to spend this money.

This needs to be emphasized: School districts will be getting more money overall in the House budget, and they’ll be getting it with no strings attached. Click here to read more.

 

Venezuelan Illegal Who Pretended to Be High Schooler Pleads Guilty. Case Puts Spotlight on Operation Take Back America.

The Venezuelan national who posed as an Ohio high school student for over a year pleaded guilty to four criminal counts Monday. The case highlights the role of a Department of Justice initiative, Operation Taking Back America, in helping fulfill the Trump administration’s promise to tackle illegal immigration.

The case involving 24-year-old Anthony Emmanuel Labrador-Sierra thrust the Northern District of Ohio into the national news cycle. Labrador-Sierra first came to the attention of law enforcement in May when he was discovered posing as a 15-year-old at Perrysburg High School. He was arrested a month later. Click here to read more.

 

How Benji’s case exposed a vet going to great lengths to change identity of a dog

TONAWANDA, N.Y. — Benji, a Yorkshire Terrier, was a godsend to Monica Crogan.

Crogan, a 57-year-old resident of the Tuscarora Indian Nation, adopted Benji in the summer of 2023 for a support dog to ease her anxiety and depression.

Benji’s energetic and social personality delighted Crogan and her grandchildren.

A year later, on July 17, 2024, Benji went missing, sending Crogan into a panic.

What happened in the next few months is a series of events described by those involved as one of the craziest, stranger-than-fiction stories of a year-long investigation involving a missing pet. Click here to read more.

Read full Article
See More
Available on mobile and TV devices
google store google store app store app store
google store google store app tv store app tv store amazon store amazon store roku store roku store
Powered by Locals